Tauroursodeoxycholic acid CAS 35807-85-3 Dietary supplement Natural product

Description:

Tauroursodeoxycholic acid[TUDCA], the more hydrophilic form of ursodeoxycholic acid[UDCA], is the more abundant naturally produced bile acid in humans. Moreover, tauroursodeoxycholic acid is found in bears with high amount and has been used for centuries as a natural remedy in some Asian countries^[1]. It has been approved in Italy and Turkey for the treatment of cholesterol gallstones and as well as being investigational drug in China, Unites States, and Italy. Tauroursodeoxycholic acid is also under investigation of its potential therapeutic effects on Primary Biliary Cirrhosis[PBC], insulin resistance, amyloidosis, Cystic Fibrosis, Cholestasis, and Amyotrophic Lateral Sclerosis. The only completed clinical trial thus far is a phase III clinical trial comparing tauroursodeoxycholic acid and ursofalk in PBC adult patients, but as of June 2013 no results of this trial have been published^[1].

Chemical formula:

Basic parameters:

What is Tauroursodeoxycholic acid used for?

Tauroursodeoxycholic acid is used to prevent and treat gallstone formation. Tauroursodeoxycholic acid is used in combination with phenylbutyric acid to treat amyotrophic lateral sclerosis (ALS) in adults.

What are the effects of Tauroursodeoxycholic acid?

As a major example, TUDCA, as a representative substance of hydrophilic bile acids, has the effect of reducing the absorption of cholesterol in the small intestine [12], thereby reducing the body's intake of dietary cholesterol, and lowering the body cholesterol content.

What is the source Tauroursodeoxycholic acid?

Tauroursodeoxycholic acid, more commonly referred to as TUDCA, is a bile salt that is found natrually occurring in the body. When regular bile salts reach the intestines, they can be metabolized by bacteria into UDCA and then later bound to a taurine molecule to become TUDCA.

Who should not take TUDCA?

Given the limited research on TUDCA supplementation during pregnancy and nursing, it's advised that pregnant or nursing women avoid it. Anyone with underlying medical conditions should speak to a doctor before using TUDCA as it may interact with other medications.

Can I drink TUDCA?

TUDCA should not be taken before drinking alcohol as the combination of alcohol and TUDCA may be more damaging to the liver than alcohol alone. It is perfectly fine to take TUDCA the next day after drinking, but it should be skipped on any day you'll be consuming alcohol.

FAQ

1. How to assure the quality of product?

We can offer you samples before you purchase large quantity.

2. What package do you use?

Usually small quantity is used by ziplock bag, for  large quantity, we use 25kg fiber drum.

3. How to deliver this product?

Small quantity usually uses Fedex, UPS, DHL etc. Large quantity is delivered by sea.

4. Is any discount?

Yes, we try to offer you the best price. 

 

References:

1. http://go.drugbank.com

2. https://www.elsevier.es

3. https://examine.com

4. https://bodybio.com › blogs › blog

5. https://doublewoodsupplements.com